TRPV2 antibody (N-Term)

Catalog No. ABIN3044039

The Rabbit Polyclonal anti-TRPV2 antibody is suitable to detect TRPV2 in samples from Human. It has been validated for WB.

Quick Overview for TRPV2 antibody (N-Term) (ABIN3044039)

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPV2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRPV2 Antibody

Binding Specificity: AA 42-624, N-Term

Purpose: Anti-VRL1/TRPV2 Antibody

Sequence: QFQGEDRKFA PQIRVNLNYR K

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-VRL1/TRPV2 Antibody (ABIN3044039). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human VRL1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRPV2

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Alternative Name: TRPV2

Background:

Synonyms: Transient receptor potential cation channel subfamily V member 2,TrpV2,Osm-9-like TRP channel 2,OTRPC2,Vanilloid receptor-like protein 1,VRL-1,TRPV2,VRL,

Tissue Specificity: Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells.

Background: TRPV2 (Transient Receptor Potential Cation Channel Subfamily V Member 2), also known as VRL1, is a protein that, in humans, is encoded by the TRPV1 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52??C. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat.

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.

Molecular Weight: 450 kDa

UniProt: Q9Y5S1

Pathways: Regulation of Cell Size