ITGB1 antibody (Extracellular Domain)

Catalog No. ABIN302617

This Rabbit Polyclonal antibody specifically detects ITGB1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for ITGB1 antibody (Extracellular Domain) (ABIN302617)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITGB1 Antibody

Binding Specificity: Extracellular Domain

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide - KLH conjugated, extracellular domain of human

Application Details

Application Notes: Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: CD29 / Integrin beta-1

Background: Integrins are a major class of cell adhesion molecules that mediate cell matrix interactions. They are composed of an alpha and a beta subunit. Beta 1 heterodimers are widely expressed and control various developmental processes, including neurogenesis, chondrogenesis, myoblast fusion, and skin and hair follicle morphogenesis.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

Gene ID: 9606

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome