Kv1.4 antibody (Middle Region)

Catalog No. ABIN3042541

Product Details anti-Kv1.4 Antibody

Target: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Binding Specificity: AA 329-344, Middle Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv1.4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 4(KCNA4) detection. Tested with WB in Human,Mouse,Rat.

Sequence: LPEFRDDRDL VMALSA

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 4(KCNA4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: potassium voltage-gated channel, shaker-related subfamily, member 4
Protein Name: Potassium voltage-gated channel subfamily A member 4

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Kv1.4(329-344aa LPEFRDDRDLVMALSA), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for Kv1.4

Target: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Alternative Name: KCNA4 (KCNA4 Products)

Synonyms: KV1.4 antibody, KCNA4 antibody, Kv1.4 antibody, DKFZp459N0126 antibody, KCHAN antibody, Kv4 antibody, RHK1 antibody, RK3 antibody, HBK4 antibody, HK1 antibody, HPCN2 antibody, HUKII antibody, KCNA4L antibody, KCNA8 antibody, PCN2 antibody, potassium voltage-gated channel subfamily A member 4 antibody, potassium voltage-gated channel subfamily A member 4 S homeolog antibody, potassium voltage-gated channel, shaker-related subfamily, member 4 antibody, KCNA4 antibody, LOC100622932 antibody, kcna4.S antibody, Kcna4 antibody

Background: Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It is mapped to 11p14.1. KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential. KCNA4 also contributes to the cardiac transient outward potassium current(Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. This gene has been shown to interact with DLG4, KCNA2 and DLG1.

Synonyms: Voltage gated K+ channel HuKII antibody|cardiac potassium channel antibody|fetal skeletal muscle potassium channel antibody|HBK 4 antibody|HBK4 antibody|HK 1 antibody|HK1 antibody|HPCN 2 antibody|HPCN2 antibody|HUK II antibody|HUKII antibody|KCNA 4 antibody|KCNA 8 antibody|KCNA4 antibody|KCNA4_HUMAN antibody|KCNA4L antibody|KCNA8 antibody|kv1.4 antibody|PCN 2 antibody|PCN2 antibody|potassium channel 2 antibody|potassium channel KCNA4 antibody|potassium channel protein antibody|Potassium voltage gated channel shaker related subfamily member 4 antibody|Potassium voltage gated channel subfamily A member 4 antibody|potassium voltage-gated channel shaker-related subfamily member 4-like antibody|Potassium voltage-gated channel subfamily A member 4 antibody|rapidly inactivating potassium channel antibody|Shaker related potassium channel Kv1.4 antibody|shaker-related potassium channel Kv1.4 antibody|type A potassium channel antibody|Voltage gated potassium channel HBK4 antibody|Voltage gated potassium channel HK1 antibody|Voltage gated potassium channel subunit Kv1.4 antibody|Voltage-gated K(+) channel HuKII antibody|voltage-gated potassium channel antibody|Voltage-gated potassium channel HBK4 antibody|Voltage-gated potassium channel HK1 antibody|voltage-gated potassium channel protein Kv1.4 antibody|Voltage-gated potassium channel subunit Kv1.4 antibody

UniProt: P22459