Kv1.4 antibody (C-Term)

Catalog No. ABIN3043264

This Rabbit Polyclonal antibody specifically detects Kv1.4 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Kv1.4 antibody (C-Term) (ABIN3043264)

Target: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv1.4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Kv1.4 Antibody

Binding Specificity: AA 609-647, C-Term

Purpose: Anti-Kv1.4/KCNA4 Antibody

Sequence: SEYLEMEEGV KESLCAKEEK CQGKGDDSET DKNNCSNAK

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Kv1.4/KCNA4 Antibody (ABIN3043264). Tested in IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.4, different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Kv1.4

Target: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Alternative Name: KCNA4

Background:

Synonyms: Potassium voltage-gated channel subfamily A member 4,HPCN2,Voltage-gated K (+) channel HuKII ,Voltage-gated potassium channel HBK4,Voltage-gated potassium channel HK1 ,Voltage-gated potassium channel subunit Kv1.4,KCNA4,KCNA4L,

Tissue Specificity: Detected in heart ventricle. .

Background: Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It is mapped to 11p14.1. KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential. KCNA4 also contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. This gene has been shown to interact with DLG4, KCNA2 and DLG1.

Molecular Weight: 73 kDa

Gene ID: 3739

UniProt: P22459