EGR2 antibody (N-Term)

Catalog No. ABIN3042850

Product Details anti-EGR2 Antibody

Target: EGR2 (Early Growth Response 2 (EGR2))

Binding Specificity: AA 153-168, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGR2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for E3 SUMO-protein ligase EGR2(EGR2) detection. Tested with WB in Human,Mouse,Rat.

Sequence: TMSQTQPDLD HLYSPP

Cross-Reactivity (Details): Predicted Cross Reactivity: rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for E3 SUMO-protein ligase EGR2(EGR2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: early growth response 2
Protein Name: E3 SUMO-protein ligase EGR2

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human EGR2(153-168aa TMSQTQPDLDHLYSPP), different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Predicted Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EGR2

Target: EGR2 (Early Growth Response 2 (EGR2))

Alternative Name: EGR2 (EGR2 Products)

Synonyms: AT591 antibody, CMT1D antibody, CMT4E antibody, KROX20 antibody, Egr-2 antibody, Krox-20 antibody, Krox20 antibody, NGF1-B antibody, Zfp-25 antibody, Zfp-6 antibody, KRX-20 antibody, cb427 antibody, egr2 antibody, id:ibd5073 antibody, krox20 antibody, krx20 antibody, wu:fb71h10 antibody, zgc:92210 antibody, frb35 antibody, early growth response 2 antibody, early growth response 2b antibody, early growth response 2a antibody, EGR2 antibody, Egr2 antibody, egr2b antibody, egr2a antibody

Background: Early growth response protein 2, also called EGR2 or E3 SUMO-protein ligase EGR2, is a protein that in humans is encoded by the EGR2 gene. This gene is mapped to 10q21.3. The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D(CMT1D), Charcot-Marie-Tooth disease type 4E(CMT4E), and with Dejerine-Sottas syndrome(DSS). E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Synonyms: AT591 antibody|CMT1D antibody|CMT4E antibody|DKFZp686J1957 antibody|E3 SUMO-protein ligase EGR2 antibody|Early growth response 2 antibody|Early growth response protein 2 antibody|EGR-2 antibody|egr2 antibody|EGR2_HUMAN antibody|FLJ14547 antibody|KROX 20 Drosophila homolog antibody|Krox 20 homolog Drosophila antibody|KROX-20, Drosophila, homolog(early growth response-2) antibody|KROX20 antibody|Krox20 protein antibody|Zinc finger protein Krox-20 antibody

UniProt: P11161