HYAL2 antibody (C-Term)

Catalog No. ABIN3043041

Product Details anti-HYAL2 Antibody

Target: HYAL2 (Hyaluronidase-2 (HYAL2))

Binding Specificity: AA 142-157, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Hyaluronidase-2(HYAL2) detection. Tested with WB in Human,Mouse,Rat. .

Sequence: VRNWQDKDVY RRLSRQ

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Hyaluronidase-2(HYAL2) detection. Tested with WB in Human,Mouse,Rat. .
Gene Name: hyaluronoglucosaminidase 2
Protein Name: Hyaluronidase-2(Hyal-2)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL2(142-157aa VRNWQDKDVYRRLSRQ), different from the related mouse and rat sequences by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HYAL2

Target: HYAL2 (Hyaluronidase-2 (HYAL2))

Alternative Name: HYAL2 (HYAL2 Products)

Synonyms: hyal2 antibody, hyal2b antibody, luca-2 antibody, luca2 antibody, xhyal2 antibody, si:dkey-42i9.14 antibody, hyal2a antibody, LUCA2 antibody, AI256841 antibody, AU020858 antibody, AW555733 antibody, oHyal2 antibody, hyaluronoglucosaminidase 2 S homeolog antibody, hyaluronoglucosaminidase 2 antibody, hyaluronoglucosaminidase 2b antibody, hyaluronoglucosaminidase 2 L homeolog antibody, hyal2.S antibody, HYAL2 antibody, hyal2b antibody, hyal2 antibody, hyal2.L antibody, Hyal2 antibody

Background: HYAL2(hyaluronoglucosaminidase 2) also known as hyaluronidase 2, LuCa-2, is an enzyme that in humans is encoded by the HYAL2 gene. HYAL2 cDNAs encode a preprotein with an N-terminal signal peptide. Northern blot analysis indicated that HYAL2 was expressed in all human tissues tested except adult brain, and Western blot analysis detected Hyal2protein in all mouse tissues examined except adult brain. The HYAL2 gene is mapped on 3p21.31. HYAL2 is a glycosylphosphatidylinositol(GPI)-anchored protein on the cell surface and serves as a receptor for entry into the cell of the jaagsiekte sheep retrovirus(JSRV). The findings of Rai et al.(2001) that HYAL2 is a GPI-anchored protein on the cell surface showed that GFP would likely be cleaved from HYAL2 during GPI addition, leaving HYAL2 on the cell surface and resulting in GFP transit to the lysosome for degradation.

Synonyms: Hyal 2 antibody|Hyal-2 antibody|Hyal2 antibody|HYAL2_HUMAN antibody|Hyaluronidase 2 antibody|Hyaluronidase 2 Precursor antibody|Hyaluronidase-2 antibody|Hyaluronoglucosaminidase 2 antibody|Hyaluronoglucosaminidase-2 antibody|LUCA 2 antibody|LUCA-2 antibody|LUCA2 antibody|Lung carcinoma protein 2 antibody|lysosomal hyaluronidase antibody|PH 20 homolog antibody|PH-20 homolog antibody|PH20 homolog antibody

UniProt: Q12891

Pathways: Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process