SDC4 antibody (C-Term)
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- Target See all SDC4 Antibodies
- SDC4 (Syndecan 4 (SDC4))
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Binding Specificity
- AA 172-198, C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SDC4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Syndecan-4(SDC4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequence
- MKKKDEGSYD LGKKPIYKKA PTNEFYA
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Syndecan-4(SDC4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: syndecan 4
Protein Name: Syndecan-4 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human Syndecan 4 (172-198aa MKKKDEGSYDLGKKPIYKKAPTNEFYA), identical to the related mouse and rat sequences.
- Isotype
- IgG
- Top Product
- Discover our top product SDC4 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat , The detection limit for Syndecan 4 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- SDC4 (Syndecan 4 (SDC4))
- Alternative Name
- SDC4 (SDC4 Products)
- Synonyms
- SYND4 antibody, AA959608 antibody, AW108331 antibody, Synd4 antibody, ryudocan antibody, syndecan-4 antibody, RATRYUDOCA antibody, RYUDOCA antibody, SDC4 antibody, sdc4l antibody, wu:fc47g09 antibody, Syndecan-4 antibody, amphiglycan antibody, syn-4 antibody, syn4 antibody, syndecan 4 antibody, syndecan 4 S homeolog antibody, syndecan 4 L homeolog antibody, SDC4 antibody, Sdc4 antibody, sdc4 antibody, sdc4.S antibody, sdc4.L antibody
- Background
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Syndecan 4 is also known as SDC4. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Synonyms: Amphiglycan antibody|Amphiglycan antibody|MGC22217 antibody|OTTHUMP00000031788 antibody|ryudocan amphiglycan antibody|Ryudocan antibody|Ryudocan core protein antibody|Ryudocan core protein antibody|SDC 4 antibody|SDC4 antibody|SDC4_HUMAN antibody|SYND 4 antibody|SYND4 antibody|syndecan 4 antibody|syndecan 4 (amphiglycan, ryudocan) antibody|syndecan proteoglycan 4 antibody|Syndecan-4 antibody|Syndecan4 antibody - Gene ID
- 6385
- UniProt
- P31431
- Pathways
- Glycosaminoglycan Metabolic Process
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