NGFB antibody (Nerve Growth Factor beta) (AA 162-173)

Details for Product anti-NGFB Antibody No. ABIN3043754, Supplier: Log in to see
Antigen
  • NGFB
  • ngfb
  • ns:zft386
  • xx:zft386
  • zgc:109730
  • hsan5
  • beta-ngf
  • Ngfb
  • Beta-NGF
  • HSAN5
  • beta-NGF
  • nerve growth factor
  • nerve growth factor b (beta polypeptide)
  • beta-Nerve growth factor
  • nerve growth factor (beta polypeptide)
  • NGF
  • ngfb
  • FPV072
  • FPV076
  • ngf
  • Ngf
Alternatives
anti-Human NGFB antibody for Enzyme Immunoassay
Epitope
AA 162-173, N-Term
15
14
11
7
5
4
2
2
2
2
2
1
1
1
1
Reactivity
Human, Rat (Rattus)
176
110
85
13
4
3
3
2
1
Host
Rabbit
137
57
10
3
2
1
Clonality
Polyclonal
Conjugate
This NGFB antibody is un-conjugated
18
7
7
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
125
122
56
29
17
17
13
13
10
8
6
4
2
2
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Purpose Rabbit IgG polyclonal antibody for Beta-nerve growth factor(NGF) detection. Tested with WB in Human,Mouse,Rat.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human NGF(162-173aa EVNINNSVFKQY), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
Sequence EVNINNSVFK QY
Isotype IgG
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Beta-nerve growth factor(NGF) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nerve growth factor(beta polypeptide)
Protein Name: Beta-nerve growth factor(Beta-NGF)
Purification Immunogen affinity purified.
Alternative Name NGF (NGFB Antibody Abstract)
Background Nerve growth factor is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. The nucleotide sequence of human and mouse beta-NGF are very similar. The beta-subunits of nerve growth factor(NGFB) have been assigned to mouse chromosome 3 and human chromosome 1p22. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. A mutation in the nerve growth factor beta gene(NGFB) causes loss of pain perception.

Synonyms: Beta nerve growth factor antibody|Beta nerve growth factor precursor antibody|Beta NGF antibody|Beta-nerve growth factor antibody|Beta-NGF antibody|HSAN5 antibody|MGC161426 antibody|MGC161428 antibody|Nerve growth factor beta antibody|Nerve growth factor beta polypeptide antibody|Nerve growth factor beta subunit antibody|NGF antibody|NGF B antibody|NGF_HUMAN antibody|NGFB antibody|NID67 antibody
UniProt P01138
Research Area Neurology, Growth Factors
Pathways NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-Nerve Growth Factor beta (NGFB) (AA 162-173), (N-Term) antibody (ABIN3043754) Anti-NGF antibody, Western blotting WB: Rat Brain Tissue Lysate
Western Blotting (WB) image for anti-Nerve Growth Factor beta (NGFB) (AA 162-173), (N-Term) antibody (ABIN3043754) Anti-NGF antibody, Western blotting Lane 1: Recombinant Human NGFB Protein 10ng Lane ...
Product cited in: Luo, Liu, Chen, Wang, Zeng, Chen, Cheng et al.: "Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 ..." in: Neural regeneration research, Vol. 7, Issue 4, pp. 302-7, 2015 (PubMed).

Lu, Liu, Zhu, Xu: "Expression of nerve growth factor and hypoxia inducible factor-1? and its correlation with angiogenesis in non-small cell lung cancer." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 359-62, 2014 (PubMed).

Li, Ma, Yi, Wang, Li, Liu, Sun, Chen, Yu, Li, Chen, Zhou: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, 2014 (PubMed).

Huang, Zhang, Xu, Li, Zhao: "Expression of nerve growth factor in the prostate of male rats in response to chronic stress and sympathetic denervation." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1237-1240, 2014 (PubMed).

Zhao, Ding, Guo, Chen: "Intrathecal lidocaine neurotoxicity: combination with bupivacaine and ropivacaine and effect of nerve growth factor." in: Life sciences, Vol. 112, Issue 1-2, pp. 10-21, 2014 (PubMed).

Li, Shu, Tang, Deng, Fu, Lv: "?-Nerve growth factor attenuates hepatocyte injury induced by D-galactosamine in vitro via TrkA NGFR." in: Molecular medicine reports, Vol. 8, Issue 3, pp. 813-7, 2013 (PubMed).

Sun, Guo, Zheng, Zhang, Li, Liu, Yin, Yang, Shu: "Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy." in: Journal of molecular neuroscience : MN, Vol. 49, Issue 1, pp. 182-93, 2012 (PubMed).

Wang, Zhao, Fan, Gong, Li, Qi, Liu: "Research on the mechanism of Zuogui Pill and Yougui Pill in promoting axonal regeneration in model rats of autoimmune encephalomyelitis." in: Chinese journal of integrative medicine, Vol. 16, Issue 2, pp. 167-72, 2010 (PubMed).

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