MALT1 antibody (C-Term)
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- Target See all MALT1 Antibodies
- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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Binding Specificity
- AA 809-824, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MALT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) detection. Tested with WB in Human.
- Sequence
- DEIPFSFSDR LRISEK
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) detection. Tested with WB in Human.
Gene Name: mucosa associated lymphoid tissue lymphoma translocation gene 1
Protein Name: Mucosa-associated lymphoid tissue lymphoma translocation protein 1 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1(809-824aa DEIPFSFSDRLRISEK).
- Isotype
- IgG
- Top Product
- Discover our top product MALT1 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MALT1 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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- Target
- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
- Alternative Name
- MALT1 (MALT1 Products)
- Synonyms
- malt1 antibody, MALT1 antibody, mlt antibody, mlt1 antibody, MLT antibody, MLT1 antibody, A630046N12 antibody, D430033E09Rik antibody, MALT paracaspase 2 antibody, MALT1 paracaspase antibody, MALT1 paracaspase S homeolog antibody, paracaspase 3 antibody, malt2 antibody, MALT1 antibody, malt1.S antibody, Malt1 antibody, PCASP3 antibody
- Background
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MALT1(Mucosa-associated lymphoid tissue lymphoma translocation protein 1), also called MLT or PARACASPASE, is a protein that in humans is encoded by the MALT1 gene. This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3(also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. Dierlamm et al.(1999) and Akagi et al.(1999) mapped the MALT1 gene to chromosome 18q21. Using mouse models, Ruland et al.(2003) demonstrated that MALT1 is essential for T-cell activation, proliferation, and IL2 production in response to T-cell receptor ligation and strictly required for signal-specific NF-kappa-B(NFKB) activation induced by the T-cell receptor but not TNF-alpha or IL1 signaling. MALT1 operates downstream of BCL10, controls the catalytic activity of the canonical I-kappa-B kinase complex, and regulates the signaling of JNK and p38 MAP kinases.
Synonyms: Caspase like protein antibody|DKFZp434L132 antibody|MALT 1 antibody|MALT associated translocation antibody|MALT lymphoma associated translocation antibody|MALT lymphoma-associated translocation antibody|Malt1 antibody|MALT1_HUMAN antibody|MLT 1 antibody|MLT antibody|MLT1 antibody|Mucosa associated lymphoid tissue lymphoma translocation gene 1 antibody|Mucosa associated lymphoid tissue lymphoma translocation protein 1 antibody|Mucosa-associated lymphoid tissue lymphoma translocation protein 1 antibody|Paracaspase antibody - Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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