CDKN2D antibody (full length)

Catalog No. ABIN306573

The Mouse Monoclonal anti-CDKN2D antibody (Clone DCS100) (ABIN306573) specifically detects CDKN2D in WB, IHC and IP. The antibody is reactive with Human samples.

Quick Overview for CDKN2D antibody (full length) (ABIN306573)

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN2D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: DCS100

Product Details anti-CDKN2D Antibody

Binding Specificity: full length

Purpose: Mouse anti Human p19 - ink4d

Cross-Reactivity: Pig

Characteristics: The immunogen for the anti-h-p19 was a his-tagged recombinant full length p19 protein recognizing a 19kD protein. The p19ink4d tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16 ink4a and p15ink4b. p19nk4d is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. It is maximally induced as cells enter S phase.

Purification: Protein A/G Chromatography

Immunogen: A his-tagged recombinant full length p19 protein recognizing a 19kD protein

Isotype: IgG1

Application Details

Application Notes: Applications: Western Blot, Immunoistochemistry, Immunoprecipitation (co-precipitates cdk4/cdk6)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for CDKN2D

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Alternative Name: p19 - ink4d

Background: Hp19, p19 ink4d, CDKN2D, Cyclin-dependent kinase 4 inhibitor D

UniProt: P55273

Pathways: Cell Division Cycle, Sensory Perception of Sound, Mitotic G1-G1/S Phases, Negative Regulation of intrinsic apoptotic Signaling