LNX1 antibody

Catalog No. ABIN307142

Product Details anti-LNX1 Antibody

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNX1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Numb-binding protein 1, Ligand of Numb-protein X 1,LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65

Purification: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the human LNX1 protein.

Application Details

Application Notes: Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for LNX1

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Alternative Name: LNX1 (LNX1 Products)

Synonyms: LNX1 antibody, fj78f06 antibody, lnx antibody, si:dkey-12h2.1 antibody, wu:fj78f06 antibody, zgc:152906 antibody, Lnx antibody, LNX antibody, MPDZ antibody, PDZRN2 antibody, ligand of numb-protein X 1 antibody, LNX1 antibody, lnx1 antibody, Lnx1 antibody

UniProt: Q8TBB1