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Details for Product No. ABIN309587

Telomeric Repeat Binding Factor 2 (TERF2) (C-Term) antibody

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Antigen
Synonyms TRF2, TRBF2, trf2, TERF2
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN309587
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-TERF2 antibody: synthetic peptide directed towards the C terminal of human TERF2
Sequence TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDR WRTMKRLGMN
Predicted Reactivity African clawed frog : 100%, Bovine : 100%, Dog : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, Rat : 100%
Characteristics This is a rabbit polyclonal antibody against TERF2. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Protein A purified
Alternative Name TERF2
Background TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Molecular Weight 55kDa
Gene ID 7014
NCBI Accession NP_005643, NM_005652
UniProt Q15554
Research Area DNA/RNA, Cell Cycle, Enzymes
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-TERF2 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Etheridge, Compton, Barrientos et al.: "Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation." in: The Journal of biological chemistry, Vol. 283, Issue 11, pp. 6935-41, 2008 (PubMed).

Alternatives for antigen "Telomeric Repeat Binding Factor 2 (TERF2)", type "Antibodies"
Hosts (25), (11), (11)
Reactivities (44), (14), (8), (2), (2), (1), (1), (1)
Applications (42), (21), (18), (14), (12), (11), (11), (4), (3), (3), (3), (1), (1), (1)
Conjugates (2), (2), (2), (1), (1)
Epitopes (5), (2), (1), (1), (1), (1), (1), (1), (1)
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