Host Cell Factor C2 (HCFC2) (C-Term) antibody

Details for Product No. ABIN309662
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Antigen
Synonyms HCF-2, HCF2, 1700129L13Rik, AU019838, D22S673, HC2, HCII, HLS2, LS2, THPH10
Epitope
C-Term
(2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(30), (15), (15), (1), (1)
Host
Rabbit
(21), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(17), (10), (4), (4), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN309662
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human HCFC2
Sequence STKSEVDETY ALPATKISRV ETHATATPFS KETPSNPVAT VKAGERQWCD
Predicted Reactivity Human : 100 %, Bovine : 90 %, Dog : 90 %, Guinea pig : 90 %, Pig : 90 %, Rabbit : 90 %, Horse : 80 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against HCFC2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HCFC2
Background HCFC2 is one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not.This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described.
Molecular Weight 87 kDa
Gene ID 29915
NCBI Accession NP_037452, NM_013320
UniProt Q9Y5Z7
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 792 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Host Cell Factor C2 (HCFC2) (C-Term) antibody WB Suggested Anti-HCFC2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
anti-Host Cell Factor C2 (HCFC2) (C-Term) antibody (2) WB Suggested Anti-HCFC2
Antibody Titration: 0.2-1 µg/mL
Positive Control: Jurkat cell lysate
Background publications Yokoyama, Wang, Wysocka et al.: "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression." in: Molecular and cellular biology, Vol. 24, Issue 13, pp. 5639-49, 2004 (PubMed).

Validation Images
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