Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (N-Term) antibody

Details for Product No. ABIN310054
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Antigen
Synonyms
HNRPM, si:ch211-197g15.1, wu:fa10g07, wu:fa98b02, hnrpm, CG9373, Dmel\\CG9373, Hrp59, cg9373, hnRNP M, hrp59, p75, CEAR, HNRNPM4, HNRPM4, HTGR1, NAGR1, 2610023M21Rik, AA409009, Hnrpm, mKIAA4193, Hnrpm ... show more
HNRPM, si:ch211-197g15.1, wu:fa10g07, wu:fa98b02, hnrpm, CG9373, Dmel\\CG9373, Hrp59, cg9373, hnRNP M, hrp59, p75, CEAR, HNRNPM4, HNRPM4, HTGR1, NAGR1, 2610023M21Rik, AA409009, Hnrpm, mKIAA4193, Hnrpm4 show less
Epitope
N-Term
(11), (11), (7), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Human, Chicken
(57), (24), (24), (14), (12)
Host
Rabbit
(39), (21)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(48), (27), (18), (17), (13), (10), (7), (7), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN310054
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human HNRPM
Sequence ATEIKMEEES GAPGVPSGNG APGPKGEGER PAQNEKRKEK NIKRGGNRFE
Predicted Reactivity Human : 100 %, Mouse : 90 %, Rat : 90 %  
Characteristics This is a rabbit polyclonal antibody against HNRPM. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HNRPM
Background HNRPM belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPM has three repeats of quasi-RRM domains that bind to RNAs. HNRPM also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.
Molecular Weight 73 kDa
Gene ID 4670
NCBI Accession NP_112480, NM_031203
UniProt P52272
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 691 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (N-Term) antibody WB Suggested Anti-HNRPM Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
Product cited in: Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

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