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Details for Product No. ABIN310358

Keratin 20 (KRT20) (Middle Region) antibody

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Antigen
Synonyms CD20, CK-20, CK20, K20, KRT21, 9030623C06Rik, Krt21, KRT20
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN310358
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-KRT20 antibody: synthetic peptide directed towards the middle region of human KRT20
Sequence DDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLG NTVNVEVDAA
Predicted Reactivity Rabbit : 92%, Dog : 84%
Characteristics This is a rabbit polyclonal antibody against KRT20. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Protein A purified
Alternative Name KRT20
Background KRT20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa.The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
Molecular Weight 48kDa
Gene ID 54474
NCBI Accession NP_061883, NM_019010
UniProt P35900
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-KRT20 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Wong, Cheung, Ma et al.: "Isolated tumor cells and circulating CK20 mRNA in pN0 colorectal cancer patients." in: International journal of surgical pathology, Vol. 16, Issue 2, pp. 119-26, 2008 (PubMed).

Alternatives for antigen "Keratin 20 (KRT20)", type "Antibodies"
Hosts (89), (76), (3), (2)
Reactivities (160), (37), (36), (11), (2), (2), (1), (1)
Applications (107), (89), (36), (32), (24), (11), (10), (10), (8), (7), (5), (4), (4), (3), (1)
Conjugates (6), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (19), (6), (3), (3), (2), (2), (1), (1), (1)
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