Alkaline Phosphatase, Placental-Like 2 (ALPPL2) (N-Term) antibody

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Antigen
Epitope
N-Term
(20), (15), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(58), (3), (3), (1)
Host
Rabbit
(50), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (3), (2), (2), (2), (2)
Application
Western Blotting (WB)
(52), (27), (22), (10), (6), (4), (4), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human ALPPL2
Sequence MQGPWVLLLL GLRLQLSLGI IPVEEENPDF WNRQAAEALG AAKKLQPAQT
Predicted Reactivity Mouse : 81 %, Rat : 71 %
Characteristics This is a rabbit polyclonal antibody against ALPPL2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name ALPPL2 (ALPPL2 Antibody Abstract)
Background There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The exact physiological function of the alkaline phosphatases is not known. ALPPL2 is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The exact physiological function of the alkaline phosphatases is not known. The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.
Molecular Weight 59 kDa
Gene ID 251
NCBI Accession NP_112603, NM_031313
UniProt P10696
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 532 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Alkaline Phosphatase, Placental-Like 2 (ALPPL2) (N-Term) antibody (ABIN310377) WB Suggested Anti-ALPPL2 Antibody Titration: 2.5ug/ml
Positive Control: ...
Background publications Nakano, Shimanuki, Matsushita et al.: "Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types." in: Biochemical and biophysical research communications, Vol. 341, Issue 1, pp. 33-8, 2006 (PubMed).