Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (C-Term) antibody

Details for Product No. ABIN310414
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Antigen
Synonyms E2-F1, L-UBC, UBCH7, UbcM4, C79827, Ubce7, UBE2L3, ube2l3l, wu:fb38h03
Epitope
C-Term
(12), (4), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Xenopus laevis, Cow (Bovine), Pig (Porcine), Zebrafish (Danio rerio), Human, Chicken
(48), (25), (25), (16), (2), (2), (2), (2), (2), (1)
Host
Rabbit
(40), (7), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(42), (20), (13), (10), (8), (6), (4), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN310414
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide directed towards the C terminal of human UBE2L3
Sequence IQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFT KKYGEKRPVD
Predicted Reactivity African clawed frog : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against UBE2L3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name UBE2L3
Background UBE2L3(ubiquitin-conjugating enzyme E2L 3) Antibody The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Molecular Weight 17 kDa
Gene ID 7332
NCBI Accession NM_003347, NP_003338
UniProt P68036
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 154 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (C-Term) antibody WB Suggested Anti-UBE2L3 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
Product cited in: Collins, Wright, Edwards et al.: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, 2004 (PubMed).

Hosts (40), (7), (5)
Reactivities (48), (25), (25), (16), (2), (2), (2), (2), (2), (1)
Applications (42), (20), (13), (10), (8), (6), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (4), (3), (2), (2), (1), (1), (1), (1)
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