UBE2L3 antibody (Ubiquitin-Conjugating Enzyme E2L 3) (AA 106-135)

Details for Product anti-UBE2L3 Antibody No. ABIN1881966, Supplier: Log in to see
Antigen
  • E2-F1
  • L-UBC
  • UBCH7
  • UbcM4
  • C79827
  • Ubce7
  • ube2l3
  • wu:fc22h11
  • zgc:86727
  • UBE2L3
  • ube2l3l
  • wu:fb38h03
  • ubiquitin conjugating enzyme E2 L3
  • ubiquitin-conjugating enzyme E2L 3
  • ubiquitin-conjugating enzyme E2L 3a
  • ubiquitin conjugating enzyme E2 L3 S homeolog
  • ubiquitin-conjugating enzyme E2L 3b
  • UBE2L3
  • Ube2l3
  • ube2l3a
  • ube2l3.S
  • ube2l3b
Epitope
AA 106-135, C-Term
40
17
10
10
7
3
3
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
124
59
54
11
11
7
7
7
6
6
6
6
4
4
2
Host
Rabbit
101
19
5
Clonality (Clone)
Polyclonal ()
Conjugate
This UBE2L3 antibody is un-conjugated
7
7
7
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
105
58
43
25
13
12
8
6
4
2
1
Options
Supplier
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Immunogen This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3.
Clone RB41666
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Plasmids, Primers & others Plasmids, Primers & others UBE2L3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name UBE2L3 (UBE2L3 Antibody Abstract)
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.

Synonyms: UBE2L3, UBCE7, UBCH7, Ubiquitin-conjugating enzyme E2 L3, L-UBC, UbcH7, Ubiquitin carrier protein L3, Ubiquitin-conjugating enzyme E2-F1, Ubiquitin-protein ligase L3
NCBI Accession NP_003338, NP_001243284, NP_001243285
UniProt P68036
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 106-135), (C-Term) antibody (ABIN1881966) UBE2L3 Antibody (C-term) (ABIN1881966) western blot analysis in K562,U87-MG,mouse NIH...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3) (AA 106-135), (C-Term) antibody (ABIN1881966) Immunohistochemical analysis of paraffin-embedded H.kidney section using UBE2L3 Antib...
Product cited in: Amidon, Hawley: "Oral bioperformance and 21st century dissolution." in: Molecular pharmaceutics, Vol. 7, Issue 5, pp. 1361, 2013 (PubMed).

Fransen, Visschedijk, van Sommeren, Fu, Franke, Festen, Stokkers, van Bodegraven, Crusius, Hommes, Zanen, de Jong, Wijmenga, van Diemen, Weersma: "Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease." in: Human molecular genetics, Vol. 19, Issue 17, pp. 3482-8, 2010 (PubMed).

Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: "Multiple common variants for celiac disease influencing immune gene expression. ..." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Kamatani, Matsuda, Okada, Kubo, Hosono, Daigo, Nakamura, Kamatani: "Genome-wide association study of hematological and biochemical traits in a Japanese population." in: Nature genetics, Vol. 42, Issue 3, pp. 210-5, 2010 (PubMed).

Han, Zheng, Cui, Sun, Ye, Hu, Xu, Cai, Huang, Zhao, Xie, Fang, Lu, Xu, Li, Pan, Deng, Zeng, Ye, Zhang, Wang, Hao, Ma, Zuo, Zhou, Du, Cheng, Yang, Shen, Li, Sheng, Zuo, Zhu, Gao, Zhang, Guo, Li et al.: "Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus...." in: Nature genetics, Vol. 41, Issue 11, pp. 1234-7, 2009 (PubMed).

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