SLC7A8 antibody (Middle Region)

Catalog No. ABIN310522

This Rabbit Polyclonal antibody specifically detects SLC7A8 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Horse, Zebrafish (Danio rerio), Dog, Rabbit and Guinea Pig.It has been mentioned in 1 publication

Quick Overview for SLC7A8 antibody (Middle Region) (ABIN310522)

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Reactivity: Human, Rat, Mouse, Cow, Horse, Zebrafish (Danio rerio), Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC7A8 Antibody

Binding Specificity: Middle Region

Sequence: PRAIFISIPL VTFVYVFANV AYVTAMSPQE LLASNAVAVT FGEKLLGVMA

Specificity: 100 % homologous to isoforms 1 (58 kDa), 2 (37 kDa), 3 (35 kDa) and 4 (48 kDa).

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC7A8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC7A8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 332 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC7A8 antibody (ABIN310522)

Romanet, Aschenbach, Pieper, Zentek, Htoo, Whelan, Mastrototaro: "Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources." in: Genes & nutrition, Vol. 16, Issue 1, pp. 14, (2021) (PubMed).

Target Details for SLC7A8

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Alternative Name: SLC7A8

Background: SLC7A8 is sodium-independent, high-affinity transport of large neutral amino acids. It has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. SLC7A8 also plays a role in basolateral (re)absorption of neutral amino acids.
Alias Symbols: LAT2, LPI-PC1
Protein Interaction Partner: SLC3A1, UBC, SLC3A2,
Protein Size: 332

Molecular Weight: 37 kDa

Gene ID: 23428

NCBI Accession: NM_182728, NP_877392