SLC7A8 antibody (AA 476-506)

Catalog No. ABIN6243302

Product Details anti-SLC7A8 Antibody

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Binding Specificity: AA 476-506

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLC7A8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 476-506 amino acids from human SLC7A8.

Clone: RB55244

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000-1:2000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SLC7A8

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Alternative Name: SLC7A8 (SLC7A8 Products)

Synonyms: LAT2 antibody, LPI-PC1 antibody, Lat2 antibody, Lat4 antibody, XAA2 antibody, lat2 antibody, lpi-pc1 antibody, 4F2LC-5 antibody, AA408822 antibody, si:ch211-14a17.3 antibody, si:zc14a17.3 antibody, slc7a8 antibody, solute carrier family 7 member 8 antibody, solute carrier family 7 member 8 L homeolog antibody, solute carrier family 7 (amino acid transporter, L-type), member 8 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 antibody, solute carrier family 7 (amino acid transporter light chain, L system), member 8b antibody, SLC7A8 antibody, Slc7a8 antibody, slc7a8.L antibody, slc7a8 antibody, slc7a8b antibody

Background: Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.

Molecular Weight: 58382

UniProt: Q9UHI5