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Details for Product No. ABIN310735

Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (C-Term) antibody

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Antigen
Synonyms CAF-1P60, CAF-I p60, CAF1, MPP7, CAF-1, CAF1A, CAF1P60, CAF-IP60, MPHOSPH7, caf-1, 2600017H24Rik, C76145, CAF-Ip60, wu:fd07c09, wu:fe36g06, wu:fv38g09, zgc:56096, CHAF1B
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN310735
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-CHAF1B antibody: synthetic peptide directed towards the C terminal of human CHAF1B
Sequence PPSSVPTSVISTPSTEEIQSETPGDAQGSPPELKRPRLDE NKGGTESLDP
Predicted Reactivity Human :100%,  
Characteristics This is a rabbit polyclonal antibody against CHAF1B. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Protein A purified
Alternative Name CHAF1B
Background Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. CHAF1B corresponds to the p60 subunit and is required for chromatin assembly after replication. CHAF1B is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
Molecular Weight 61kDa
Gene ID 8208
NCBI Accession NP_005432, NM_005441
UniProt Q13112
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CHAF1B antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Alternatives for antigen "Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B)", type "Antibodies"
Hosts (13), (7)
Reactivities (18), (6), (4), (1), (1), (1), (1), (1)
Applications (15), (8), (5), (3), (2), (2)
Epitopes (2), (2), (2), (1), (1), (1)
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