Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (C-Term) antibody

Details for Product No. ABIN310735
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Antigen
Synonyms CAF-1P60, CAF-I p60, CAF1, MPP7, CAF-1, CAF1A, CAF1P60, CAF-IP60, MPHOSPH7, caf-1, 2600017H24Rik, C76145, CAF-Ip60, wu:fd07c09, wu:fe36g06, wu:fv38g09, zgc:56096, CHAF1B
Epitope
C-Term
(2), (2), (2), (1), (1), (1)
Reactivity
Human
(20), (8), (2), (1), (1), (1), (1), (1)
Host
Rabbit
(17), (7)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(20), (8), (7), (4), (4), (2), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN310735
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen Synthetic peptide directed towards the C terminal of human CHAF1B
Sequence PPSSVPTSVISTPSTEEIQSETPGDAQGSPPELKRPRLDE NKGGTESLDP
Predicted Reactivity Human :100 %,  
Characteristics This is a rabbit polyclonal antibody against CHAF1B. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name CHAF1B
Background Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. CHAF1B corresponds to the p60 subunit and is required for chromatin assembly after replication. CHAF1B is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
Molecular Weight 61 kDa
Gene ID 8208
NCBI Accession NM_005441, NP_005432
UniProt Q13112
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 559 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (C-Term) antibody anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (C-Term) antibody
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (C-Term) antibody (2) anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (C-Term) antibody (Image 2)
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Hosts (17), (7)
Reactivities (20), (8), (2), (1), (1), (1), (1), (1)
Applications (20), (8), (7), (4), (4), (2), (2), (2)
Epitopes (2), (2), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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