RARRES3 antibody (Middle Region)

Catalog No. ABIN310822

This Rabbit Polyclonal antibody specifically detects RARRES3 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for RARRES3 antibody (Middle Region) (ABIN310822)

Target: RARRES3 (Retinoic Acid Receptor Responder (Tazarotene Induced) 3 (RARRES3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RARRES3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RARRES3 Antibody

Binding Specificity: Middle Region

Purpose: RARRES3 Antibody - middle region

Sequence: FSVLSNSAEV KRERLEDVVG GCCYRVNNSL DHEYQPRPVE VIISSAKEMV

Predicted Reactivity: Human: 93%

Characteristics: This is a rabbit polyclonal antibody against RARRES3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RARRES3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110402

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RARRES3

Target: RARRES3 (Retinoic Acid Receptor Responder (Tazarotene Induced) 3 (RARRES3))

Alternative Name: RARRES3

Background:

Background Information: Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES3 is thought act as a tumor suppressor or growth regulator.Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.

Gene Name: Retinoic acid receptor responder (tazarotene induced) 3

Alternative Symbols: RIG1, TIG3, HRSL4, HRASLS4, PLAAT-4, RARRES3, PLA1/2-3

Protein Name: Retinoic acid receptor responder protein 3

Molecular Weight: 18kDa

Gene ID: 5920

NCBI Accession: NP_004576

UniProt: Q9UL19