RARRES3 antibody (AA 80-160)

Catalog No. ABIN7231808

The Rabbit Polyclonal anti-RARRES3 antibody (ABIN7231808) specifically detects RARRES3 in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for RARRES3 antibody (AA 80-160) (ABIN7231808)

Target: RARRES3 (Retinoic Acid Receptor Responder (Tazarotene Induced) 3 (RARRES3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RARRES3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-RARRES3 Antibody

Binding Specificity: AA 80-160

Purpose: Rabbit Anti-TIG3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TIG3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TIG3 protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RARRES3

Target: RARRES3 (Retinoic Acid Receptor Responder (Tazarotene Induced) 3 (RARRES3))

Alternative Name: TIG3

Background: Retinoic acid receptor responder protein 3, HRAS-like suppressor 4, HRSL4, RAR-responsive protein TIG3, Retinoid-inducible gene 1 protein, Tazarotene-induced gene 3 proteinRetinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.

Molecular Weight: 18kD

Gene ID: 5920

UniProt: Q9UL19