CD51 antibody (PE)

Catalog No. ABIN316874

Product Details anti-CD51 Antibody (PE)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD51 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Characteristics: Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

Immunogen: cultured LAK cells from Balb/c mice.

Clone: RMV-7

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: 1/10.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 1 mL distilled water

Concentration: 0.1mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0,09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: aPOISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Expiry Date: 12 months

Target Details for CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: CD51 / ITGAV (ITGAV Products)

Synonyms: 1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody

Background: CD51 is a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the intergrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing.Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

UniProt: P43406

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex