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NPPB antibody (N-Term)

NPPB Reactivity: Human WB, EIA Host: Mouse Monoclonal 5-00E-002 unconjugated
Catalog No. ABIN317050
  • Target See all NPPB Antibodies
    NPPB (Natriuretic Peptides B (NPPB))
    Binding Specificity
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-32, N-Term
    Reactivity
    • 29
    • 6
    • 4
    • 2
    • 1
    Human
    Host
    • 24
    • 12
    Mouse
    Clonality
    • 24
    • 12
    Monoclonal
    Conjugate
    • 26
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPPB antibody is un-conjugated
    Application
    • 19
    • 14
    • 12
    • 12
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects an epitope located at the C-terminal (amino acids 26-32) of the brain natriuretic peptide (BNP), a secreted protein which is a member of the natriuretic peptide family. This antibody also detects proBNP.
    Characteristics
    Synonyms: NPPB
    Purification
    Purified IgG prepared by affinity chromatography on Protein A
    Immunogen
    Human synthetic BNP.
    Clone
    5-00E-002
    Isotype
    IgG1
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    Discover our top product NPPB Primary Antibody
  • Application Notes
    ELISA. Western Blot: detects a band of approximately 4 kDa when using synthetic BNP and a bandof 14 kDa when using recombinant proBNP. Immunoassay.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0mg/mL
    Buffer
    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by
    Expiry Date
    12 months
  • Target
    NPPB (Natriuretic Peptides B (NPPB))
    Alternative Name
    Natriuretic Peptides B (NPPB Products)
    Synonyms
    BNP1 antibody, NPPB antibody, BNP antibody, Bnf antibody, AA408272 antibody, natriuretic peptide B antibody, natriuretic peptide type B antibody, NPPB antibody, Nppb antibody
    Background
    BNP is a cardiac hormone, which is synthesised as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure.Synonyms: NPPB
    Gene ID
    4879
    UniProt
    P16860
    Pathways
    Hormone Activity
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