Meningioma 1 antibody
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- Target See all Meningioma 1 (MN1) Antibodies
- Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Meningioma 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects endogenous levels of MN1 protein.(region surrounding Lys850)
- Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product MN1 Primary Antibody
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- Application Notes
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Western Blot: 1/500-1/1000. ELISA: 1/40000-1/60000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))
- Alternative Name
- MN1 (MN1 Products)
- Synonyms
- MGCR antibody, MGCR1 antibody, MGCR1-PEN antibody, dJ353E16.2 antibody, MN1 proto-oncogene, transcriptional regulator antibody, MN1 antibody
- Background
- The MN1 gene, which resides on chromosome 22, encodes a 1,319 amino acid protein. The ETV6/TEL gene has been reported to fuse to MN1. The MN1-TEL fusion protein, encoded by the translocation (12,22)(p13,q11) in myeloid leukemia, is a transcription factor with transforming activity. Defects in MN1 (meningioma 1) may be a cause of meningiomas, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord.Synonyms: Probable tumor suppressor protein MN1, meningioma 1
- Gene ID
- 4330
- NCBI Accession
- NP_002421
- UniProt
- Q10571
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