B4GALT3 antibody

Catalog No. ABIN317820

Product Details anti-B4GALT3 Antibody

Target: B4GALT3 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 3 (B4GALT3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B4GALT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: β-1,4-Gal-T3 antibody detects endogenous levels of β-1,4-Gal-T3 protein.(region surrounding Phe304)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for B4GALT3

Target: B4GALT3 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 3 (B4GALT3))

Alternative Name: B4GALT3 (B4GALT3 Products)

Synonyms: beta4Gal-T3 antibody, 9530061M23Rik antibody, AA104562 antibody, AW125175 antibody, ESTM26 antibody, ESTM6 antibody, R74981 antibody, b4Gal-T3 antibody, beta-1,4-galactosyltransferase 3 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 S homeolog antibody, UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 antibody, B4GALT3 antibody, b4galt3.S antibody, B4galt3 antibody

Background: Several oligosaccharide structures and protein glycoconjugate types are found in nature. Homologous glycosyltransferase (GT) gene families catalyze the formation of glycosidic linkages. The β-1,3 galactosyltransferase(β3GalT) gene family encodes a set of type II transmembrane glycoproteins that are catalytically diverse and use different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine ) to catalyze the addition of an activated monosaccharide to a terminal lactose. The protein coding sequences for β-1,3-Gal-T genes comprise a single exon and are distantly related to the Drosophila Brainiac gene. The β-1,4-galactosyltransferase (β4GalT) gene family encodes type II membrane-bound glycoproteins that show exclusive specificity for the donor substrate, UDP-galactose. β-1,4Gal-T genes transfer galactose in a β-1,4 linkage to similar acceptor sugars, each gene has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures.Synonyms: 4-GalTase 3, 4-galactosyltransferase 3, Beta-1, Beta-1, Beta4Gal-T3, UDP-Gal:beta-GlcNAc beta-1, UDP-galactose:beta-N-acetylglucosamine beta-1, b4Gal-T3

Molecular Weight: approx. 49 kDa

Gene ID: 8703

NCBI Accession: NP_001186802

UniProt: O60512

Pathways: Glycosaminoglycan Metabolic Process