ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
ndrg3 antibody, ndrg4 antibody, smap-8 antibody, NDRG4 antibody, D8Bwg1337e antibody, Ndr1-rs antibody, Ndr4 antibody, R74996 antibody, SMAP-8 antibody, BDM1 antibody, SMAP8 antibody, Bdm1 antibody, smap8 antibody, NDRG family member 4 antibody, NDRG family member 4 S homeolog antibody, NDRG family member 3 antibody, N-myc downstream regulated gene 4 antibody, NDRG4 antibody, ndrg4.S antibody, ndrg3 antibody, Ndrg4 antibody
Background
The N-Myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65 % homology. NDRG4 (NDRG family member 4), also known as SMAP8 (smooth muscle-associated protein 8) or BDM1 (brain development-related molecule 1), is a 352 amino acid cytoplasmic protein that belongs to the NDRG family. Expressed specifically in brain and heart, NDRG4 is thought to function as a regulator of mitogenic signaling in vascular smooth muscle cells. Additionally, NDRG4 may play a role in early postnatal development and may mediate the differentiation and subsequent function of neuronal cells. NDRG4 is expressed as six isoforms (the first three of which are designated NDRG4- BVar, NDRG4-B and NDRG4-H) due to alternative splicing events.Synonyms: BDM1, Brain development-related molecule 1, KIAA1180