This antibody recognises human luteinizing hormone, a gonadotrophic hormone found in the anterior lobe of the pituitary gland. TSH: 20 % hCG: 6 % FSH: 6 % Prolactin: 0.1 % hPL: 0.1 %
Purification
Purified IgG prepared by affinity chromatography on Protein G
Immunogen
Highly purified human pituitary luteinizing hormone.
LHB
ELISA, D, LF, IA, T
Host: Mouse
Monoclonal
unconjugated
Application Notes
IRMA. Radioimmunoassays: >1/50,000 initial dilution in 125I RIA overnight assay. ELISA: Has been used for coating and also as a capture antibody in a two site assay inconjunction with other monoclonal antibodies. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.Synonyms: LH