PPP1R13L antibody (Isoform 1)

Catalog No. ABIN318866

Product Details anti-PPP1R13L Antibody

Target: PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

Binding Specificity: AA 780-797, Isoform 1

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R13L antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antiobdy detects inhibitor of apoptosis stimulating protein of p53 (iASPP).

Purification: Purified

Immunogen: Synthetic peptide corresponding amino acids 780-797 of human iASPP (isoform 1) protein.

Isotype: IgG

Application Details

Application Notes: ELISA: 1: 40000 - 1: 160000. ,Western Blot: 1: 1000 - 1: 5000, detects a bands of approximately 100 and 50 kDacorresponding to iASPP isoforms 1 and 2 respectively.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2 containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPP1R13L

Target: PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

Alternative Name: PPP1R13L (PPP1R13L Products)

Synonyms: AV260376 antibody, IASPP antibody, Nkip1 antibody, wa3 antibody, zgc:113058 antibody, NKIP1 antibody, RAI antibody, RAI4 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 13 like antibody, protein phosphatase 1, regulatory subunit 13 like antibody, protein phosphatase 1 regulatory subunit 13 like antibody, protein phosphatase 1 regulatory subunit 13 like L homeolog antibody, Ppp1r13l antibody, ppp1r13l antibody, PPP1R13L antibody, ppp1r13l.L antibody

Background: IASPP plays a central role in regulation of apoptosis and transcription via its interaction with NFkB and p53 proteins. At present, the iASPP gene is thought to encode three isoforms, isoform 1 is predominantly located in the cytoplasm, whilst isoforms 2 and 3 are nuclear proteins. iASPP is highly expressed in the heart, placenta and prostate. iASPP has been shown to have oncogenic properties in human breast carcinomas.Synonyms: IASPP, Inhibitor of ASPP protein, NFkB-interacting protein 1, NKIP1, PPP1R13B-like protein, PPP1R13BL, RAI, RelA-associated inhibitor

Gene ID: 10848

NCBI Accession: NP_001135974

UniProt: Q8WUF5