Dynamin 1 antibody (pSer778)
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- Target See all Dynamin 1 (DNM1) Antibodies
- Dynamin 1 (DNM1)
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Binding Specificity
- pSer778
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Chicken
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Host
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Sheep
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Clonality
- Polyclonal
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Conjugate
- This Dynamin 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody is specific for Dynamin when phosphorylated at serine 778.
- Purification
- Affinity chromatography
- Immunogen
- Synthetic phosphopeptide corresponding to an amino acid sequence within dynamin which includes phosphorylated Ser778.
- Isotype
- IgG
- Top Product
- Discover our top product DNM1 Primary Antibody
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- Application Notes
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Western Blot: 1: 1000, detects a band of approximately 95 kDa in rat hippocampus lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Dynamin 1 (DNM1)
- Alternative Name
- Dynamin-1 (DNM1 Products)
- Synonyms
- DNM antibody, Dnm antibody, AI838169 antibody, Ftfl antibody, mKIAA4093 antibody, dnm antibody, DNM1 antibody, Dnm1 antibody, dnm1 antibody, si:dkey-246l19.2 antibody, dynamin 1 antibody, dynamin-1 antibody, dynamin 1a antibody, DNM1 antibody, Dnm1 antibody, BACOIKO008_37 antibody, PTRG_07818 antibody, PTRG_08097 antibody, dnm1 antibody, LOC100168088 antibody, LOC100199205 antibody, dnm1a antibody
- Background
- Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.Synonyms: DNM, DNM1
- Gene ID
- 140694
- NCBI Accession
- NP_542420
- UniProt
- P21575
- Pathways
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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