Cytokeratin 13 antibody

Catalog No. ABIN335223

Product Details anti-Cytokeratin 13 Antibody

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Mab 2D7 specifically recognizes keratin K13 (54 kD polypeptide, formerly designated cytokeratin 13) present in non-cornifying squamous epithelia and in transitional epithelium of the bladder. Epidermal cell culture studies have shown that keratin K13 expression is involved in either the number or the strength of desmosomal contacts between suprabasal cells of stratified squamous epithelia. Reacts with Human, most mammals incl. mouse, rat, rabbit.

Purification: Supernatant

Immunogen: Keratin preparation from human esophagus.

Clone: 2D7

Isotype: IgG2b

Application Details

Application Notes: Immunofluorescence. Immunohistochemistry on frozen sections: 1:5 - 1:10. Immunoblotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

References for anti-Cytokeratin 13 antibody (ABIN335223)

van Dorst, van Muijen, Litvinov, Fleuren: "The limited difference between keratin patterns of squamous cell carcinomas and adenocarcinomas is explicable by both cell lineage and state of differentiation of tumour cells." in: Journal of clinical pathology, Vol. 51, Issue 9, pp. 679-84, (1999) (PubMed).

Van Niekerk, Ramaekers, Hanselaar, Aldeweireldt, Poels: "Changes in expression of differentiation markers between normal ovarian cells and derived tumors." in: The American journal of pathology, Vol. 142, Issue 1, pp. 157-77, (1993) (PubMed).

Bauwens, De Groot, Ramaekers, Veldman, Huizing: "Expression of intermediate filament proteins in the adult human vestibular labyrinth." in: The Annals of otology, rhinology, and laryngology, Vol. 101, Issue 6, pp. 479-86, (1992) (PubMed).

Smedts, Ramaekers, Troyanovsky, Pruszczynski, Link, Lane, Leigh, Schijf, Vooijs: "Keratin expression in cervical cancer." in: The American journal of pathology, Vol. 141, Issue 2, pp. 497-511, (1992) (PubMed).

van Niekerk, Boerman, Ramaekers, Poels: "Marker profile of different phases in the transition of normal human ovarian epithelium to ovarian carcinomas." in: The American journal of pathology, Vol. 138, Issue 2, pp. 455-63, (1991) (PubMed).

Smedts, Ramaekers, Robben, Pruszczynski, van Muijen, Lane, Leigh, Vooijs: "Changing patterns of keratin expression during progression of cervical intraepithelial neoplasia." in: The American journal of pathology, Vol. 136, Issue 3, pp. 657-68, (1990) (PubMed).

Weikel, Wagner, Moll: "Characterization of subcolumnar reserve cells and other epithelia of human uterine cervix. Demonstration of diverse cytokeratin polypeptides in reserve cells." in: Virchows Archiv. B, Cell pathology including molecular pathology, Vol. 54, Issue 2, pp. 98-110, (1988) (PubMed).

van Muijen, Ruiter, Franke, Achtstätter, Haasnoot, Ponec, Warnaar: "Cell type heterogeneity of cytokeratin expression in complex epithelia and carcinomas as demonstrated by monoclonal antibodies specific for cytokeratins nos. 4 and 13." in: Experimental cell research, Vol. 162, Issue 1, pp. 97-113, (1986) (PubMed).

Target Details for Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Alternative Name: Cytokeratin 13 / Keratin K13 (KRT13 Products)

Synonyms: krt13 antibody, CK13 antibody, K13 antibody, Ka13 antibody, Krt-1.13 antibody, Krt1-13 antibody, ck13 antibody, k13 antibody, keratin 24 antibody, keratin 13 antibody, keratin 13, type I S homeolog antibody, krt24 antibody, KRT13 antibody, Krt13 antibody, krt13.S antibody, k13 antibody

UniProt: P13646