Cytokeratin 13 antibody (AA 269-458)

Catalog No. ABIN7268090

The Rabbit Polyclonal anti-Cytokeratin 13 antibody is suitable to detect Cytokeratin 13 in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for Cytokeratin 13 antibody (AA 269-458) (ABIN7268090)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Cytokeratin 13 Antibody

Binding Specificity: AA 269-458

Purpose: Cytokeratin 13 (KRT13) Rabbit pAb

Sequence: DLTRVLAEMR EQYEAMAERN RRDAEEWFHA KSAELNKEVS TNTAMIQTSK TEITELRRTL QGLEIELQSQ LSMKAGLENT VAETECRYAL QLQQIQGLIS SIEAQLSELR SEMECQNQEY KMLLDIKTRL EQEIATYRSL LEGQDAKMIG FPSSAGSVSP RSTSVTTTSS ASVTTTSNAS GRRTSDVRRP

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 269-458 of human Cytokeratin 13 (Cytokeratin 13 (KRT13)) (NP_705694.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Alternative Name: KRT13

Background: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been described.,KRT13,CK13,K13,WSN2,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Cytokeratin,Keratin,KRT13

Molecular Weight: 38kDa/45kDa/49kDa

Gene ID: 3860

UniProt: P13646