Calcitonin antibody

Catalog No. ABIN336941

Product Details anti-Calcitonin Antibody

Target: Calcitonin (Calca)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Synthetic peptide from human Calcitonin conjugated to carrier protein

Application Details

Application Notes: Immunohistochemistry (IHC) 1:50-1:200 using polymer or streptavidin biotin system. For 30 minute at room temperature. The optimum dilution should be determined by the individual lab. General Reference: Holm, R, J Pathology, 158: 213-217,1989 Positive Control: Human thyroid or medulary carcinoma. Cellular Localization: Cytoplasmic.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Total immunoglobulin fraction in10 mM PO4, 150 mM NaCl, pH 7.4, 0.05% sodium azide. HostRabbit ReagentConc. antibody

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Calcitonin

Target: Calcitonin (Calca)

Alternative Name: Calcitonin (Calca Products)

Synonyms: calcitonin-related polypeptide alpha antibody, CALCA antibody

Background: Calcitonin is a 32-amino acid polypeptide hormone that is produced in human primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body It acts to reduce blood calcium (Ca 2+ ), opposing the effects of parathyroid hormone (PTH) Calcitonin staining can detect C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors.