MUC2 antibody

Catalog No. ABIN336957

Product Details anti-MUC2 Antibody

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Immunogen: 23 amino acid MUC2 peptide

Application Details

Application Notes: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. The optimum dilution should be determined by the individual lab. Positive Control: Human colon carcinoma, LS 174 T colon cancer cell line. Cellular Localization: Cytoplasmic, perinuclear staining of goblet cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Total immunoglobulin fractionin10 mM PO4, 150 mM NaCl, pH 7.4, 0.05% sodium azide HostRabbit Intended Use Immunohistochemistry (IHC) and Immunocytchemistry (ICC)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MUC2

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Alternative Name: MUC2 (MUC2 Products)

Synonyms: 2010015E03Rik antibody, MCM antibody, wnn antibody, MLP antibody, MUC-2 antibody, SMUC antibody, HH-Muc antibody, mucin 2 antibody, mucin 2, oligomeric mucus/gel-forming antibody, mucin-2 antibody, Muc2 antibody, MUC2 antibody, LOC100724045 antibody

Background: Mucin 2, oligomeric mucus/gel-forming, also known as MUC2, is a human intestinal mucin gene. This gene is expressed in colon, small intestine, colonic tumors, bronchus, cervix, gall bladder, and possibly other tissues. Mucins are high molecular weight glycoproteins having oligosaccharides attached to serine or threonine residue of the apomucin protein backbone by O-glycosidic linkages. This antibody stains normal colon and colonic carcinomas where it produces intense perinuclear staining in goblet cells. It also reacts with normal and neoplastic breast tissues and with prostate carcinoma.