alpha Fetoprotein antibody

Catalog No. ABIN336969

Product Details anti-alpha Fetoprotein Antibody

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Fetoprotein antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Molecular Weight: 70 kDa.

Immunogen: Purified human AFP

Application Details

Application Notes: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. The optimum dilution should be determined by the individual lab. Positive Control: Human fetal liver, tonsil. Cellular Localization: Cytoplasmic.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is supplied with 1% BSA in PBS with 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Alternative Name: a-Fetoprotein (AFP Products)

Synonyms: FETA antibody, HPAFP antibody, alpha fetoprotein antibody, alpha-fetoprotein antibody, AFP antibody, Afp antibody

Background: Alpha fetoprotein (AFP) is a 70 kDa glycoprotein (700 aa) produced by the yolk sac, liver and intestinal tract during fetal life. AFP is a useful marker for detection of numerous developmental defects (open neural tube defect), hepatocarcinoma and endodermal sinus tumor (germ cell and yolk sac). Traces of AFP are found in normal adult sera and in greater concentrations in maternal, fetal and amniotic fluid.

Pathways: C21-Steroid Hormone Metabolic Process