NEIL1 antibody (AA 378-390)

Catalog No. ABIN337008

The Goat Polyclonal anti-NEIL1 antibody (ABIN337008) specifically detects NEIL1 in ELISA, IHC and IHC (p). The antibody is reactive with Human samples.

Quick Overview for NEIL1 antibody (AA 378-390) (ABIN337008)

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NEIL1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NEIL1 Antibody

Binding Specificity: AA 378-390

Specificity: Human NEIL1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla (100%) Bovine, Pig (92%) Monkey, Bat (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-DIPSLEPEGTSAS from the C-terminus of human NEIL1 (NP_078884.2). Percent identity by BLAST analysis: Human, Gorilla (100%), Bovine, Pig (92%), Monkey, Bat (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:16000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for NEIL1

Target: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Alternative Name: NEIL1

Background: Name/Gene ID: NEIL1

Synonyms: NEIL1, DNA glycosylase/AP lyase Neil1, Endonuclease VIII, Endonuclease 8-like 1, Endonuclease VIII-like 1, FPG1, HFPG1, Nei homolog 1, NEI1, Nei-like protein 1, NEH1

Gene ID: 79661

NCBI Accession: NP_078884

UniProt: Q96FI4

Pathways: DNA Damage Repair