Retinoblastoma Binding Protein 4 antibody (AA 1-425)

Catalog No. ABIN342231

The Mouse Monoclonal anti-Retinoblastoma Binding Protein 4 antibody (Clone 3-255) (ABIN342231) specifically detects Retinoblastoma Binding Protein 4 in WB, IF and IP. The antibody is reactive with Human samples.

Quick Overview for Retinoblastoma Binding Protein 4 antibody (AA 1-425) (ABIN342231)

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoblastoma Binding Protein 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 3-255

Product Details anti-Retinoblastoma Binding Protein 4 Antibody

Binding Specificity: AA 1-425

Specificity: Recognizes full-length human RbAp48 (48 kD) and RbAp46 (46 kD), nuclear proteins first identified by their ability to interact with the C- terminus of retinoblastoma protein (Rb). The amino acid sequences of RbAp48 and RbAp46 are highly homologous Both Rb Ap48 and RbAp46 interact with human histone deacetlyase Hd1 and can bind to histone H4.

Purification: Protein G purified

Immunogen: GST fusion protein containing the complete coding region (aa 1-425) of RbAp48 expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG2a

Application Details

Application Notes: Approved: IF (0.2 - 1 μg/mL), IP, WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Store at -70°C, avoid freeze/thaw cycles.

Target Details for Retinoblastoma Binding Protein 4

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Alternative Name: RBBP4 / RBAP48

Background: Name/Gene ID: RBBP4

Synonyms: RBBP4, CAF-I p48, CAF-1 subunit C, CAF-I 48 kDa subunit, MSI1 protein homolog, Histone-binding protein RBBP4, NURF55, RBBP-4, RBAP48

Gene ID: 5928

UniProt: Q09028

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus