GRIK3 antibody (AA 203-216)

Catalog No. ABIN343069

Product Details anti-GRIK3 Antibody

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Binding Specificity: AA 203-216

Reactivity: Human, Mouse, Rat, Hamster, Rabbit

Host: Goat

Clonality: Polyclonal

Conjugate: This GRIK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human GRIK3.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit, Opossum (100%) Monkey, Panda, Bovine, Dog, Bat, Horse, Pig (93%) Platypus (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KIRQLPIDSDDSRP from an internal region of human GRIK3 (NP_000822.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit, Opossum (100%), Monkey, Panda, Bovine, Dog, Bat, Horse, Pig (93%), Platypus (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:64000, 0.3 - 1 μg/mL), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western Blot: Approx. 110kD band observed in Mouse Brain and Rat Brain lysates (calculated MW of 104kD according to Human NP_000822.2, and to Rat NP_001106187.1). Recommended concentration: 0.3-1 μg/mL. An additional band of unknown identity was also consistently observed at 39kD. This band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GRIK3

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Alternative Name: GRIK3 / GLUR7 (GRIK3 Products)

Synonyms: GRIK3 antibody, eaa5 antibody, glr7 antibody, glur7 antibody, 9630027E11 antibody, GluK3 antibody, GluR7-3 antibody, Glur-7 antibody, Glur7 antibody, GluR7 antibody, gluR-7 antibody, EAA5 antibody, GLR7 antibody, GLUR7 antibody, GluR7a antibody, glutamate ionotropic receptor kainate type subunit 3 antibody, glutamate receptor, ionotropic, kainate 3 L homeolog antibody, glutamate receptor, ionotropic, kainate 3 antibody, GRIK3 antibody, grik3.L antibody, Grik3 antibody

Background: Name/Gene ID: GRIK3
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIK3, GluR-7, GLUR7, EAA5, GLR7, Glutamate receptor 7, GluK3, GluR7a

Gene ID: 2899

NCBI Accession: NP_000822

UniProt: Q13003

Pathways: Synaptic Membrane