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Details for Product No. ABIN350087

ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) antibody

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Antigen
Synonyms
ASP, APG5, APG5L, hAPG5, APG5-LIKE, Apg5l, Atg5l, Paddy, C88337, AW319544, 2010107M05Rik, 3110067M24Rik, apg5l, zgc:100934, ATATG5, ATG5, AUTOPHAGY 5, MKP11.20, MKP11_20, CG1643, DmAtg5, Dmel\\CG1643, ... show more
Reactivity
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350087
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from human autophagy protein 5 (ATG5, ASP, APG5, APG5L, hAPG5) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in mouse, xenopus and chicken.
Isotype IgG
Specificity Appears to be specific for ATG5.
Purity IgG
Alternative Name Autophagy protein 5 (ATG5, APG5)
Background ATG5 is an important element forautophagy and may also play an important role in the apoptotic process. Following conjugation to ATG12, the conjugate participates in the formation of autophagosome. While the mRNA is ubiquitously transcribed its expression is highly upregulated in apoptotic cells. Also known as: APG5-like, ATG5, ASP, APG5, APG5L, hAPG5, apoptosis-specific protein.
UniProt Q9H1Y0
Research Area Autophagy
Application Notes IHC, WB. Use at a concentration of 10-50 µg/ml. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Grand, Milner, Mustoe et al.: "A novel protein expressed in mammalian cells undergoing apoptosis." in: Experimental cell research, Vol. 218, Issue 2, pp. 439-51, 1995 (PubMed).

Hammond, Brunet, Johnson et al.: "Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast." in: FEBS letters, Vol. 425, Issue 3, pp. 391-5, 1998 (PubMed).

Mizushima, Sugita, Yoshimori et al.: "A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 33889-92, 1999 (PubMed).

Schmeiser, Armstrong, Hammond et al.: "Assignment of the yeast APG5 human homologue APG5L to chromosome band 6q21 by fluorescence in situ hybridisation." in: Cytogenetics and cell genetics, Vol. 87, Issue 3-4, pp. 213-4, 2000 (PubMed).

Simonsen, Birkeland, Gillooly et al.: "Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes." in: Journal of cell science, Vol. 117, Issue Pt 18, pp. 4239-51, 2004 (PubMed).

Alternatives for antigen "ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5)", type "Antibodies"
Hosts (96), (24), (14), (4), (3)
Reactivities (128), (72), (60), (37), (33), (18), (17), (16), (13), (13), (2), (1), (1), (1), (1)
Applications (124), (56), (53), (25), (20), (10), (10), (6), (3), (2), (1), (1)
Conjugates (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (32), (11), (10), (10), (4), (4), (2), (1), (1), (1), (1), (1), (1)
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