A synthetic peptide from the GAT domain of mouse GGA2 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat.
GGA2
Reactivity: Human
WB
Host: Mouse
Polyclonal
unconjugated
Application Notes
IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice
Avoid freeze and thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane, Peripheral membrane protein. Endosome membrane, Peripheral membrane protein.,Vesicle Transport,ADP-ribosylation factor-binding protein GGA2, Golgi-localized, gamma ear-containing, ARF-binding protein 2, Gamma-adaptin-related protein 2