GGA3 antibody

Catalog No. ABIN350342

The Rabbit Polyclonal anti-GGA3 antibody has been validated for WB and IHC. It is suitable to detect GGA3 in samples from Human.

Quick Overview for GGA3 antibody (ABIN350342)

Target: GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GGA3 Antibody

Purpose: Rabbit antibody to GGA3

Specificity: Specific for GGA3.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from the VHS domain of human GGA3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat mouse chicken.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for GGA3

Target: GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))

Alternative Name: GGA3

Background: FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. SUBCELLULAR LOCATION: Golgi apparatus trans-Golgi network membrane, Peripheral membrane protein. Endosome membrane, Peripheral membrane protein. TISSUE SPECIFICITY: Ubiquitously expressed.

UniProt: Q9NZ52