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Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10) (C-Term) antibody

Details for Product No. ABIN351013, Supplier: Login to see
Antigen
  • tmp21
  • P24(DELTA)
  • S31I125
  • S31III125
  • TMP21
  • Tmp-21-I
  • p23
  • 1110014C03Rik
  • Tmp21
  • p24delta1
  • fe06g04
  • wu:fb98e10
  • wu:fe06g04
  • zgc:85681
Epitope
C-Term
41
13
10
5
2
2
1
1
Reactivity
Mouse (Murine), Rat (Rattus), Human
86
42
42
4
1
1
1
1
1
1
1
1
Host
Rabbit
72
15
2
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
64
43
25
15
11
4
2
Supplier
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Immunogen A synthetic peptide from the c-terminal of TMP21 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in many species including rat and mouse.
Isotype IgG
Specificity Specific for TMP21.
Alternative Name TMP21 (TMED10 Antibody Abstract)
Background Function: Involved in vesicular protein trafficking.
Subcellular location: Golgi apparatus membrane, Single-pass type I membrane protein, Lumenal side. Melanosome.
Tissue specificity: Ubiquitous. Also known as: TEMP21, 21 kDatransmembrane-trafficking protein,transmembrane protein Tmp21, Tmp-21-I, p24delta, TMED10, TMEDA.
Research Area Signaling, Alzheimer's Disease
Pathways
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Chi, Valencia, Hu et al.: "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes." in: Journal of proteome research, Vol. 5, Issue 11, pp. 3135-44, 2006 (PubMed).

Wu, MacCoss, Mardones et al.: "Organellar proteomics reveals Golgi arginine dimethylation." in: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2907-19, 2004 (PubMed).

Heilig, Eckenberg, Petit et al.: "The DNA sequence and analysis of human chromosome 14. ..." in: Nature, Vol. 421, Issue 6923, pp. 601-7, 2003 (PubMed).

Blum, Feick, Puype et al.: "Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17183-9, 1996 (PubMed).

Sherrington, Rogaev, Liang et al.: "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. ..." in: Nature, Vol. 375, Issue 6534, pp. 754-60, 1995 (PubMed).