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Details for Product No. ABIN351153

Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (C-Term), (4th Cytoplasmic Loop) antibody

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Antigen
Synonyms TRP5, CCE2, TRP-5, Trrp5, trp, trpc5, wu:fi73f08, Trpc5, TRPC5
Epitope
»Alternatives C-Term, 4th Cytoplasmic Loop
Reactivity
»Alternatives Rat (Rattus), Mouse (Murine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN351153
Quantity 150 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from c-terminal region of mouse Autophagy protein 5 (ATG5, APG5) conjugated to an immunogenic carrier protein has been used as the antigen.
Specificity Specific for ATG5.
Purity IgG
Alternative Name TRPC5
Background Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.
Subunit: Interacts with NHERF.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in brain with higher levels in fetal brain. Also known as: Short transient receptor potential channel 5, TrpC5, Htrp-5, trp5, TRP5.
UniProt Q99J83
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
Sossey-Alaoui, Lyon, Jones et al.: "Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca2+ entry channel." in: Genomics, Vol. 60, Issue 3, pp. 330-40, 1999 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Alternatives for antigen "Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5)", type "Antibodies"
Hosts (14), (14), (3)
Reactivities (23), (14), (10), (1), (1), (1)
Applications (29), (15), (6), (6), (4), (3), (3), (3), (3), (2), (1)
Epitopes (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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