Xenopus TRPN1 (NompC, Putative Transient Receptor Potential Channel) (AA 250-300) antibody

Details for Product No. ABIN351233
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AA 250-300
Immunohistochemistry (IHC), Western Blotting (WB)
(1), (1)
Pubmed 1 reference available
Catalog no. ABIN351233
Quantity 500 µg
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Immunogen A synthetic peptide from AA 250-300 of Xenopus TRPN1 conjugated to an immunogenic carrier protein was used as the antigen.
Specificity Specific for TRPM8.
Purification IgG
Alternative Name TRPN1
Background Function: May function as an ion-channel regulator. May function with PKD2L1 as heteromeric taste channels.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in a subset of taste receptor cells distinct from those involved in bitter, sweet and umami taste. Expressed in circumvallate and foliate taste buds, but not in surrounding non-gustatory lingual epithelium cells. Expressed in testis. Also known as: Putative transient receptor potential channel, nompC.
UniProt Q7Z2W7
Research Area Neurology, Metabolism
Application Notes Use at a concentration of 10-50 µg/mL.
The optimal working concentration should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General Shin, Adams, Paukert et al.: "Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 35, pp. 12572-7, 2005 (PubMed).

Hosts (1)
Reactivities (1)
Applications (1), (1)
Epitopes (1)
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