PINK1 antibody

Catalog No. ABIN356391

The Mouse Monoclonal anti-PINK1 antibody (Clone 38CT18-7) (ABIN356391) specifically detects PINK1 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for PINK1 antibody (ABIN356391)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PINK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 38CT18-7

Product Details anti-PINK1 Antibody

Specificity: This antibody is specific to PINK1.

Characteristics: Synonyms: PTEN-induced putative kinase protein 1, PARK6, BRPK, PINK-1, Serine/threonine-proteinkinase PINK1, mitochondrial, Parkinson disease (autosomal recessive) 6

Immunogen: Recombinant PINK1 protein.

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/500-1/2000. Immunohistochemistry: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Expiry Date: 12 months

Target Details for PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Alternative Name: PINK1

Background: Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.Synonyms: BRPK, PARK6, PINK-1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6, Serine/threonine-protein kinase PINK1, mitochondrial

Gene ID: 65018

UniProt: Q9BXM7

Pathways: Autophagy