UBE4B antibody (N-Term)

Catalog No. ABIN357483

Product Details anti-UBE4B Antibody

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects UBE4B at N-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBE4B.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for UBE4B

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Alternative Name: UBE4B (UBE4B Products)

Synonyms: ufd2a antibody, E4 antibody, HDNB1 antibody, UBOX3 antibody, UFD2 antibody, UFD2A antibody, 4930551I19Rik antibody, 4933406G05Rik antibody, AU014668 antibody, D4Bwg0973e antibody, UFD2a antibody, Ufd2p antibody, mKIAA0684 antibody, ubiquitination factor E4B antibody, putative ubiquitin conjugation factor E4 B antibody, ubiquitin conjugation factor E4 B antibody, ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) antibody, Ube4b antibody, LINJ_30_1070 antibody, LBRM_30_1130 antibody, Tsp_12732 antibody, Tsp_01624 antibody, ube4b antibody, UBE4B antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.Synonyms: HDNB1, Homozygously deleted in neuroblastoma 1, KIAA0684, UFD2, Ubiquitin conjugation factor E4 B, Ubiquitin fusion degradation protein 2

Molecular Weight: 133275 Da

Gene ID: 10277, 9606

UniProt: O95155