anti-CPT1B antibody (Carnitine Palmitoyltransferase 1B (Muscle)) (C-Term)

Details for Product anti-CPT1B Antibody No. ABIN357772
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Synonyms CPTIB, AV080368, Mcp-1, cpt1al, zgc:103709, CPT1B, MGC147544, CPT1-M, CPT1M, CPTI, CPTI-M, M-CPT1, MCCPT1, MCPT1, CPT1, M-CPTI, Cpt1, Cpt1-m, Cpti, Cpti-m, M-cpti, CPT-IB
(49), (16), (14), (12), (8), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1)
(99), (20), (12), (1), (1), (1), (1), (1)
(84), (20), (2)
This CPT1B antibody is un-conjugated
(8), (8), (8), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(70), (69), (42), (10), (10), (9), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CPT1B.
Isotype Ig
Specificity This antibody is specific to CPT1B/CPT1-M (C-term).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name CPT1B / CPT1-M (CPT1B Antibody Abstract)
Background CPT1B is a member of the carnitine/choline acetyltransferase family, and is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria.Synonyms: Carnitine O-palmitoyltransferase 1, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein, KIAA1670, muscle isoform
Molecular Weight 87801 Da
Gene ID 1120, 9606
UniProt Q92523
Pathways AMPK Signaling
Application Notes ELISA: 1/1,000. Western blot: 1/50-1/200. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Image no. 1 for anti-CPT1B antibody (Carnitine Palmitoyltransferase 1B (Muscle)) (C-Term) (ABIN357772) anti-Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B) (C-Term) antibody
Image no. 2 for anti-CPT1B antibody (Carnitine Palmitoyltransferase 1B (Muscle)) (C-Term) (ABIN357772) anti-Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B) (C-Term) antibody (Image 2)
Background publications Dai, Zhu, Woldegiorgis: "Leucine-764 near the extreme C-terminal end of carnitine palmitoyltransferase I is important for activity." in: Biochemical and biophysical research communications, Vol. 301, Issue 3, pp. 758-63, 2003 (PubMed).

van der Leij, Cox, Jackson et al.: "Structural and functional genomics of the CPT1B gene for muscle-type carnitine palmitoyltransferase I in mammals." in: The Journal of biological chemistry, Vol. 277, Issue 30, pp. 26994-7005, 2002 (PubMed).

Hirosawa, Nagase, Murahashi et al.: "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 8, Issue 1, pp. 1-9, 2001 (PubMed).

Yamazaki, Shinohara, Kajimoto et al.: "Novel expression of equivocal messages containing both regions of choline/ethanolamine kinase and muscle type carnitine palmitoyltransferase I." in: The Journal of biological chemistry, Vol. 275, Issue 41, pp. 31739-46, 2000 (PubMed).

Britton, Mackey, Esser et al.: "Fine chromosome mapping of the genes for human liver and muscle carnitine palmitoyltransferase I (CPT1A and CPT1B)." in: Genomics, Vol. 40, Issue 1, pp. 209-11, 1997 (PubMed).

Catalog No. ABIN357772
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