CPT1B antibody (AA 533-772)

Catalog No. ABIN6138978

Product Details anti-CPT1B Antibody

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Binding Specificity: AA 533-772

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SYQVAKALAD DVELYCFQFL PFGKGLIKKC RTSPDAFVQI ALQLAHFRDR GKFCLTYEAS MTRMFREGRT ETVRSCTSES TAFVQAMMEG SHTKADLRDL FQKAAKKHQN MYRLAMTGAG IDRHLFCLYL VSKYLGVSSP FLAEVLSEPW RLSTSQIPQS QIRMFDPEQH PNHLGAGGGF GPVADDGYGV SYMIAGENTI FFHISSKFSS SETNAQRFGN HIRKALLDIA DLFQVPKAYS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 533-772 of human CPT1B (NP_004368.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-CPT1B antibody (ABIN6138978)

Guan, Chen, Wang, Zhang, Fan, Gao, Jiao, Fu, Sun, Yu, Huang, Bi: "Effects of carnitine palmitoyltransferases on cancer cellular senescence." in: Journal of cellular physiology, Vol. 234, Issue 2, pp. 1707-1719, (2019) (PubMed).

Yu, Zhang, Cui, Wang, Na, Zhu, Li, Xu, Yang, Christian, Liu: "Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment." in: Biochimica et biophysica acta, Vol. 1853, Issue 5, pp. 918-28, (2015) (PubMed).

Target Details for CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Alternative Name: CPT1B (CPT1B Products)

Synonyms: CPT1-M antibody, CPT1M antibody, CPTI antibody, CPTI-M antibody, M-CPT1 antibody, MCCPT1 antibody, MCPT1 antibody, CPT-IB antibody, M-CPTI antibody, CPT1 antibody, CPTIB antibody, cpt1al antibody, zgc:103709 antibody, CPT1B antibody, MGC147544 antibody, Cpt1 antibody, Cpt1-m antibody, Cpti antibody, Cpti-m antibody, M-cpti antibody, carnitine palmitoyltransferase 1B antibody, carnitine palmitoyltransferase 1B (muscle) antibody, carnitine palmitoyltransferase 1B L homeolog antibody, carnitine palmitoyltransferase 1b, muscle antibody, CPT1B antibody, Cpt1b antibody, cpt1b antibody, cpt1b.L antibody

Background: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.,CPT1B,CPT1-M,CPT1M,CPTI,CPTI-M,M-CPT1,MCCPT1,MCPT1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,Endocrine and metabolic diseases,Obesity,Cardiovascular,Heart,Cardiac metabolism,Lipids,Fatty Acids,CPT1B

Molecular Weight: 66 kDa/78 kDa/83 kDa/87 kDa

Gene ID: 1375

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process