CPT1B antibody (AA 501-600)

Catalog No. ABIN708851

There is 1 publication for this product available. The Rabbit Polyclonal anti-CPT1B antibody is suitable to detect CPT1B in samples from Human. It has been validated for WB, IHC (fro), IF (cc), IF (p) and IHC (p).

Quick Overview for CPT1B antibody (AA 501-600) (ABIN708851)

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CPT1B Antibody

Binding Specificity: AA 501-600

Purpose: CPT1B Polyclonal Antibody

Specificity: This antibody should detect the four Isoforms variants of CPT1B created by alternative splicing.

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CPT1B

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CPT1B antibody (ABIN708851)

Huebbe, Dose, Schloesser, Campbell, Glüer, Gupta, Ibrahim, Minihane, Baines, Nebel, Rimbach: "Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization- studies in gene targeted replacement mice." in: Molecular nutrition & food research, (2014) (PubMed).

Target Details for CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Alternative Name: CPT1B

Background:

Synonyms: Carnitine O-palmitoyltransferase 1, muscle isoform, CPT1-M, Carnitine O-palmitoyltransferase I, muscle isoform, CPT I, CPTI-M, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein, CPT1B, KIAA1670

Background: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].

Gene ID: 1375

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process